01 - Pat catfish fillets dry with paper towels to remove excess moisture.
02 - In a shallow dish, combine buttermilk and hot sauce. Add catfish fillets, turning to coat evenly. Let marinate for 10 minutes.
03 - In a separate shallow dish, whisk together cornmeal, flour, paprika, garlic powder, onion powder, cayenne pepper, salt, and black pepper until well blended.
04 - Pour vegetable oil into a large skillet or deep fryer. Heat to 350°F, maintaining temperature throughout frying.
05 - Remove catfish from buttermilk mixture, allowing excess liquid to drip off. Dredge each fillet in the cornmeal mixture, pressing firmly to ensure even coating.
06 - Fry fillets in batches, cooking 3 to 4 minutes per side until golden brown and fish flakes easily with a fork. Transfer to paper towels to drain excess oil.
07 - Arrange fried catfish on a serving platter. Garnish with fresh lemon wedges and chopped parsley. Serve immediately while hot and crispy.